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Anti-nfkbib Antibody (MOM-18444)

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human nfkbib Antibody MOM-18444 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody is against Human NFKBIB, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • NFKBIB
  • Type
  • IgG
  • Immunogen
  • Purified recombinant fragment of Human IKB beta expressed in E. Coli.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in Neut, ELISA, FC, IP, ICC and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
  • Function
  • protein binding; signal transducer activity; transcription coactivator activity;
  • Synonyms
  • NFKBIB; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; NF-kappa-B inhibitor beta; IKBB; TRIP9; ikB-B; TRIP-9; ikB-beta; ikappaBbeta; NF-kappa-BIB; I-kappa-B-beta; TR-interacting protein 9; thyroid receptor-interacting protein 9

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