Anti-p2rx7 Antibody scFv

Cat

MOM-18457-S(P)

Product Overview

Recombinant Mouse Antibody scFv Fragment is bind to Human P2RX7, expressed in E. coli

Target

P2RX7

Type

scFv

Species Reactivity

Human

Expression Host

E. coli

Applications

Suitable for use in ELISA, WB, Neut and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>95.0% as determined by analysis by RP-HPLC.

Storage

Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Antigen Description

The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.

Function

ATP binding; ATP binding; extracellular ATP-gated cation channel activity; ion channel activity; lipopolysaccharide binding; protein homodimerization activity; purinergic nucleotide receptor activity; receptor activity; receptor binding;

Gene ID

5027

Synonyms

P2RX7; purinergic receptor P2X, ligand-gated ion channel, 7; P2X purinoceptor 7; MGC20089; P2X7; ATP receptor; P2Z receptor; P2X7 receptor; purinergic receptor P2X7 variant A

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