Anti-psca Antibody Fab

Cat

MOM-18604-F(P)

Product Overview

Recombinant Mouse Antibody Fab Fragment is specific to Human PSCA, expressed in E. coli

Target

PSCA

Type

Fab

Immunogen

The details of the immunogen for this antibody are not available.

Species Reactivity

Human

Expression Host

E. coli

Applications

Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>95.0% as determined by analysis by RP-HPLC.

Storage

Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

Antigen Description

PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.

Gene ID

8000

Synonyms

PSCA; prostate stem cell antigen; PRO232;

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