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Anti-rora Antibody Fab (MOM-18487-F(P))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human rora Antibody Fab Fragment MOM-18487-F(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment binds selectively to Human RORA, expressed in E. coli
  • Target
  • RORA
  • Type
  • Fab
  • Immunogen
  • Recombinant fragment, corresponding to amino acids 136-236 of Human ROR alpha + beta + gamma
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Purity
  • Purity >95% by SDS-PAGE.
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • ROR alpha, beta and gamma are members of the NR1 subfamily of nuclear hormone receptors. They can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. ROR alpha binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. ROR beta is required for normal postnatal development of rod and cone photoreceptor cells.
  • Function
  • ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; zinc ion binding;
  • Synonyms
  • RORA; RAR-related orphan receptor A; nuclear receptor ROR-alpha; NR1F1; ROR1; ROR2; ROR3; RZRA; ROR-alpha; nuclear receptor RZR-alpha; transcription factor RZR-alpha; retinoid-related orphan receptor alpha; nuclear receptor subfamily 1 group F member 1; thyroid hormone nuclear receptor alpha variant 4; retinoic acid receptor-related orphan receptor alpha; RZR-ALPHA; MGC119326; MGC119329; DKFZp686M2414

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