Anti-tenascin c, st2146 Antibody

Cat

MOM-18208

Product Overview

Recombinant Mouse Antibody is specific to Human Tenascin C, expressed in Chinese Hamster Ovary cells(CHO)

Target

Tenascin C

Type

Mouse IgG2

Immunogen

The details of the immunogen for this antibody are not available.

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in WB, ELISA, FC, IP, FuncS, IF, Neut and most other immunological methods.

Specificity

Tested positive against native antigen.

Protein Construction

Immunoglobulin G2b, anti-[human tenascin C (TNC, hexabrachion, HBX) Mus musculus] monoclonal antibody ST2146; gamma2b heavy chain (Mus musculus VH [8.8.13]-IGHG2B*02 from clone ST2146) (135-219")-disulfide with kappa light chain (Mus musculus V-KAPPA [11.

Predicted N terminal

H chain: EIQLQQS; L Chain: DIVMTQA

Purity

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

Storage

Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

Antigen Description

Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.

Function

Receptor binding; Syndecan binding

Gene ID

3371

Synonyms

GP; JI; TN; HXB; GMEM; TN-C; 150-225; tenascin; GP 150-225; cytotactin; neuronectin; myotendinous antigen; hexabrachion (tenascin); tenascin-C isoform 14/AD1/16; glioma-associated-extracellular matrix antigen; Miotendinous antigen

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