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Recombinant Mouse Antibody Fab Fragment is bind to Human TGFBR2, expressed in Chinese Hamster Ovary cells(CHO)
Recombinant human TGF beta Receptor II extracellular domain
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Tested positive against native antigen.
>95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Transforming Growth Factor beta Receptor II (TGFBR2) belongs to the serine-threonine kinase family. It is involved in regulating cell proliferation and differentiation and extracellular matrix production and acts as a signal transducer. It phosphorylates TGFBR1 upon binding to its ligand, TGF-beta. TGFBR1 in turn phosphorylates the cytoplasmic effectors of the pathway, known as SMADs.
ATP binding; SMAD binding; glycosaminoglycan binding; metal ion binding; nucleotide binding; protein binding; contributes_to protein binding; receptor activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta binding; transforming growth factor beta binding; transforming growth factor beta-activated receptor activity; transforming growth factor beta-activated receptor activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity; type I transforming growth factor beta receptor binding; type I transforming growth factor beta receptor binding; type III transforming growth factor beta receptor binding;