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Anti-tgfbr2 Antibody Fab (MOM-18503-F(P))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human tgfbr2 Antibody Fab Fragment MOM-18503-F(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment binds selectively to Human TGFBR2, expressed in E. coli
  • Target
  • TGFBR2
  • Type
  • Fab
  • Immunogen
  • Recombinant human TGF beta Receptor II extracellular domain
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

BACKGROUND

  • Antigen Description
  • Transforming Growth Factor beta Receptor II (TGFBR2) belongs to the serine-threonine kinase family. It is involved in regulating cell proliferation and differentiation and extracellular matrix production and acts as a signal transducer. It phosphorylates TGFBR1 upon binding to its ligand, TGF-beta. TGFBR1 in turn phosphorylates the cytoplasmic effectors of the pathway, known as SMADs.
  • Function
  • ATP binding; SMAD binding; glycosaminoglycan binding; metal ion binding; nucleotide binding; protein binding; contributes_to protein binding; receptor activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta binding; transforming growth factor beta binding; transforming growth factor beta-activated receptor activity; transforming growth factor beta-activated receptor activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity; type I transforming growth factor beta receptor binding; type I transforming growth factor beta receptor binding; type III transforming growth factor beta receptor binding;
  • Synonyms
  • TGFBR2; transforming growth factor, beta receptor II (70/80kDa); MFS2, transforming growth factor, beta receptor II (70 80kD); TGF-beta receptor type-2; tbetaR-II; TGF-beta receptor type II; TGF-beta type II receptor; TGF-beta receptor type IIB; transforming growth factor-beta receptor type II; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor II (70/80kDa) isoform 1; transforming growth factor, beta receptor II (70/80kDa) isoform 2; AAT3; FAA3; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII

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