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Anti-tnfrsf10d Antibody Fab (MOM-18513-F(E))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human tnfrsf10d Antibody Fab Fragment MOM-18513-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment is directed against Human TNFRSF10D, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • TNFRSF10D
  • Type
  • Fab
  • Immunogen
  • Recombinant human DcR2/Fc chimera
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Purity
  • >95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

BACKGROUND

  • Antigen Description
  • Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
  • Function
  • TRAIL binding; binding; receptor activity; transmembrane signaling receptor activity;
  • Synonyms
  • TNFRSF10D; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily member 10D; CD264; DcR2; TRAILR4; TRUNDD; TRAIL receptor 4; decoy receptor 2; decoy with truncated death domain; TNF receptor-related receptor for TRAIL; TRAIL receptor with a truncated death domain; TNF-related apoptosis-inducing ligand receptor 4; DCR2; TRAIL-R4

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