Anti-tnfrsf10d Antibody Fab

Cat

MOM-18513-F(P)

Product Overview

Recombinant Mouse Antibody Fab Fragment is against Human TNFRSF10D, expressed in E. coli

Target

TNFRSF10D

Type

Fab

Immunogen

Recombinant human DcR2/Fc chimera

Species Reactivity

Human

Expression Host

E. coli

Applications

Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

Purity >95% by SDS-PAGE.

Storage

Store at -20°C. Avoid multiple freeze/thaw cycles.

Antigen Description

Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.

Function

TRAIL binding; binding; receptor activity; transmembrane signaling receptor activity;

Gene ID

8793

Synonyms

TNFRSF10D; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily member 10D; CD264; DcR2; TRAILR4; TRUNDD; TRAIL receptor 4; decoy receptor 2; decoy with truncated death domain; TNF receptor-related receptor for TRAIL; TRAIL receptor with a truncated death domain; TNF-related apoptosis-inducing ligand receptor 4; DCR2; TRAIL-R4

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