Anti-vegfa Antibody Fab (MOM-18630-F(E))
|Recombinant Anti-Human vegfa Antibody Fab Fragment
- Product Overview
- Recombinant Mouse Antibody Fab Fragment is directed against Human VEGFA, expressed in Chinese Hamster Ovary cells(CHO)
- The details of the immunogen for this antibody are not available.
- Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
- Specific Activity
- Tested positive against native antigen.
- >95.0% as determined by analysis by SDS-PAGE.
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
- Antigen Description
- Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
- cell surface binding; chemoattractant activity; cytokine activity; cytokine activity; extracellular matrix binding; fibronectin binding; growth factor activity; growth factor activity; heparin binding; heparin binding; platelet-derived growth factor receptor binding; protein binding; protein heterodimerization activity; protein homodimerization activity; receptor agonist activity; vascular endothelial growth factor receptor 1 binding; vascular endothelial growth factor receptor 2 binding; vascular endothelial growth factor receptor binding;
- VEGFA; vascular endothelial growth factor A; vascular endothelial growth factor , VEGF; VEGF A; VPF; vascular permeability factor; VEGF; MVCD1; MGC70609
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.