Anti-vtcn1 Antibody Fab

Cat

MOM-18285-F(P)

Product Overview

Recombinant Mouse Antibody Fab Fragment is specific to Human VTCN1, expressed in E. coli

Target

VTCN1

Type

Fab

Immunogen

Human B7H4

Species Reactivity

Human

Expression Host

E. coli

Applications

Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.

Storage

Store at -20°C. Avoid multiple freeze/thaw cycles.

Antigen Description

Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.

Function

receptor binding;

Gene ID

79679

Synonyms

VTCN1; V-set domain containing T cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; B7 family member; H4; B7 superfamily member 1; B7 H4; B7H4; B7S1; B7X; FLJ22418; B7 family member, H4; T cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; immune costimulatory protein B7-H4; B7-H4; B7h.5; VCTN1; PRO1291; RP11-229A19.4

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