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Recombinant Mouse Antibody scFv Fragment is bind to C. albicans, expressed in E. coli
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Immunoglobulin scFv fragment, anti-(heat shock protein 90 homolog from C. albicans (yeast)), methionylalanyl-[human monoclonal HSP90mab VH domain (120 residues)]-tris[(tetraglycyl)seryl]-[human monoclonal HSP90mab V-KAPPA domain (107 residues)]-[arginyltr
Predicted N terminal
>95.0% as determined by analysis by SDS-PAGE.
Store at -20°C. Avoid multiple freeze/thaw cycles.
Monoclonal antibody binds to HSP90 of Candida albicans. It is intended to treat invasive Candida infection in combination with amphotericin B.
C. albicans is the most frequently isolated fungal pathogen of humans, affecting immunocompromised patients ranging from premature infants to AIDS sufferers. Systemic infections have an attributed mortality of 30-50%. C. albicans is a diploid organism which has eight sets of homologous chromosomes. It has a genome of approximately 16 Mb (haploid), about 30% greater than S. cerevisiae (baker's yeast).
C albicans; C. albicans; Thrush; Candida albicans HSP90