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Recombinant Anti-EDN1 Mab (HOM-19227)

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Anti-Human EDN1 Monoclonal Antibody HOM-19227 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant humanized antibody expressed in CHO binding to human EDN1.
  • Target
  • EDN1
  • Type
  • Human IgG
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • ELISA, WB, IHC, FCM, IP, IF. Optimal dilutions/concentrations should be determined by the end user.
  • Clone
  • Monoclonal
  • Molecular Weight
  • 145.41 kDa
  • Purity
  • >95.0% as determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store it under sterile conditions at -20 °C upon receiving. Recommend to pack the antibody into smaller quantities for optimal storage.
  • Stability
  • Samples are stable for up to twelve months from date of receipt at - 20°C and are stable for six months at 4 °C.
  • Ship
  • 2-8°C, BLUE ICE

BACKGROUND

  • Antigen Description
  • ET-1 is the most potent member of the ET family, which consists of the isopeptides ET-1, ET-2, and ET-3. The primary translation product of the ET-1 gene, prepro-ET-1 (212 amino acids), is cleaved by an intracellular endopeptidase releasing big ET-1 (38 amino acids). The biologically inactive big ET-1 is secreted primarily by endothelial cells and undergoes further processing by ET-converting enzymes (ECEs).
  • Function
  • cytokine activity; endothelin A receptor binding; endothelin B receptor binding; endothelin B receptor binding; hormone activity;
  • Synonyms
  • EDN1; endothelin 1; endothelin-1; ET1; preproendothelin-1; PPET1; HDLCQ7;

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