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Recombinant Anti-Hemojuvelin Mab (HOM-19322)

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Anti-Human Hemojuvelin Monoclonal Antibody HOM-19322 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant humanized antibody expressed in CHO binding to human Hemojuvelin.
  • Target
  • HFE2
  • Type
  • Human IgG
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • ELISA, WB, IHC, FCM, IP, IF. Optimal dilutions/concentrations should be determined by the end user.
  • Clone
  • Monoclonal
  • Molecular Weight
  • 145.41 kDa
  • Purity
  • >95.0% as determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store it under sterile conditions at -20 °C upon receiving. Recommend to pack the antibody into smaller quantities for optimal storage.
  • Stability
  • Samples are stable for up to twelve months from date of receipt at - 20°C and are stable for six months at 4 °C.
  • Ship
  • 2-8°C, BLUE ICE

BACKGROUND

  • Antigen Description
  • Hemojuvelin (HJV/RGMc/HFE2) is a membrane-bound and soluble protein in mammals that is responsible for the iron overload condition known as juvenile hemochromatosis in humans, a severe form of hemochromatosis. In humans, the hemojuvelin protein is encoded by the HFE2 gene. HJV is also called RGMc, a member of a three gene family (in vertebrates) called the repulsive guidance molecules. Both RGMa and RGMb are found in the nervous system while RGMc is found in skeletal muscle and the liver.
  • Synonyms
  • HFE2; hemochromatosis type 2 (juvenile); hemojuvelin; haemojuvelin; HFE2A; HJV; JH; repulsive guidance molecule c; RGMC; RGM domain family member C; hemochromatosis type 2 protein; MGC23953;

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