Recombinant Anti-Hemojuvelin Mab

Cat

HOM-19322

Product Overview

Recombinant humanized antibody expressed in CHO binding to human Hemojuvelin.

Target

HFE2

Type

Human IgG

Species Reactivity

Human

Expression Host

CHO

Applications

ELISA, WB, IHC, FCM, IP, IF. Optimal dilutions/concentrations should be determined by the end user.

Clone

Monoclonal

Molecular Weight

145.41 kDa

Purity

>95.0% as determined by analysis by RP-HPLC & analysis by SDS-PAGE.

Storage

Store it under sterile conditions at -20 °C upon receiving. Recommend to pack the antibody into smaller quantities for optimal storage.

Stability

Samples are stable for up to twelve months from date of receipt at - °C and are stable for six months at 4 °C.

Ship

2-8°C, BLUE ICE

Antigen Description

Hemojuvelin (HJV/RGMc/HFE2) is a membrane-bound and soluble protein in mammals that is responsible for the iron overload condition known as juvenile hemochromatosis in humans, a severe form of hemochromatosis. In humans, the hemojuvelin protein is encoded by the HFE2 gene. HJV is also called RGMc, a member of a three gene family (in vertebrates) called the repulsive guidance molecules. Both RGMa and RGMb are found in the nervous system while RGMc is found in skeletal muscle and the liver.

Gene ID

148738

Synonyms

HFE2; hemochromatosis type 2 (juvenile); hemojuvelin; haemojuvelin; HFE2A; HJV; JH; repulsive guidance molecule c; RGMC; RGM domain family member C; hemochromatosis type 2 protein; MGC23953;

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