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Recombinant Human C-Terminal Fragment of Kinesin Heavy Chain (CRP0849)

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human C-Terminal Fragment of Kinesin Heavy Chain CRP0849 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Human C-Terminal Fragment of Kinesin Heavy Chain produced in E. coli has a molecular mass of approximately 22 KDa.
  • Purity
  • >95% as determined by SDS-PAGE.
  • Storage
  • Inclusion Body.
  • Recombinant Human C-Terminal Fragment of Kinesin Heavy Chain
    PDB rendering based on 2gry.

BACKGROUND

  • Antigen Description
  • The kinesin family of motor proteins comprises at least two forms of conventional kinesin, and they are encoded by different genes and designated as ubiquitous kinesin, which is expressed in all cells and tissues, and neuronal kinesin, which is expressed exclusively in neuronal cells. While the kinesin heavy chain contains motor activity, evidence suggests that the kinesin light chain is involved in either modulation of kinesin heavy chain activity or in cargo binding. The motor protein kinesin is a heterotetramer composed of two heavy chains of approximately 120 kDa and two light chains of approximately 65 kDa. Kinesin motor activity is dependent on the presence of ATP and microtubules. rh-cKHC is a C-terminal fragment of uKHC with a histidine-tagged expressed in E. coli.
  • Function
  • ATP binding, microtubule motor activity, nucleotide binding
  • Gene ID
  • 3796
  • Synonyms
  • HK2; KIF2; Kinesin-2; Kinesin, heavy chain, 2; Kinesin-like protein KIF2A; kinesin heavy chain member 2; kinesin heavy chain member 2A

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