Close
Close

Recombinant Human Chemokine (C-C motif) ligand 16 /HCC-4 (CRP08111)

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Chemokine (C-C motif) ligand 16 /HCC-4 CRP08111 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Human HCC-4/CCL16 produced in E. coli is a single, non-glycosylated polypeptide chain containing 97 amino acids and having a molecular mass of 11.2 kDa.
  • Specificity
  • Fully biologically active when compared to standard. Determined by its ability to chemoattract total human monocytes using a concentration range of 10.0 -100.0 ng/ml.
  • Endotoxin
  • Less than 1EU/mg of rHuHCC-4/CCL16 as determined by LAL method.
  • Purity
  • >97% by SDS-PAGE and HPLC analyses.
  • Storage
  • This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
  • Reconstitution
  • We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.

BACKGROUND

  • Antigen Description
  • Human HCC-4, also named NCC-4, liver-expressed chemokine (LEC), and lymphocyte and monocyte chemoattractant (LMC), is a novel CC chemokine identified through bioinformatics. HCC-4 cDNA encodes a 120 amino acid (aa) residue precursor protein with a 23 aa residue predicted signal peptide that is cleaved to generate a 97 aa residue mature protein. HCC-4 is distantly related to other CC chemokines, exhibiting less than 30% sequence identity. Among these CC chemokines, HCC-4 has the most similarity to HCC-1. Two potential polyadenylation signals are present on the human HCC-4 gene, and as a result, two transcripts containing approximately 1,500 base pairs and 500 base pairs have been detected. HCC-4 is expressed weakly by some lymphocytes, including NK cells, T cells, and some T cell clones. The expression of HCC-4 in monocytes is highly upregulated in the presence of IL-10.
  • Function
  • chemoattractant activity;chemokine activity.
  • Gene ID
  • 6360
  • Synonyms
  • LEC; LMC; NCC4; CKb12; HCC-4; LCC-1; Mtn-1; NCC-4; SCYL4; ILINCK; SCYA16; MGC117051; CCL16_HUMAN; C-C motif chemokine 16 [Precursor]; Small-inducible cytokine A16;IL-10-inducible chemokine;Chemokine LEC;Liver-expressed chemokine;Monotactin-1;Chemokine CC-4;Lymphocyte and monocyte chemoattractant.

Related Products

All listed customized services & products are for research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use.

Online Inquiry

Verification code
Click image to refresh the verification code.

CONTACT US

USA: 45-1 Ramsey Road, Shirley, NY 11967, USA
Europe: Heidenkampsweg 58, 20097 Hamburg, Germany
Call us at:
USA: 1-631-381-2994
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us
Copyright © 2007 - 2020 Creative Biolabs. All Rights Reserved