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Recombinant Human Glia Maturation Factor beta (CRP0869)

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Glia Maturation Factor beta CRP0869 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Human Glia Maturation Factor beta produced in E.coli is a single non-glycosylated polypeptide chain containing 141 amino acids and having a molecular mass of approximately 16.5KDa.
  • Specificity
  • The biological activity was determined by the does-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors yielding an ED50 <0.5ng/ml.
  • Endotoxin
  • rHuGMF-β as determined by LAL method.
  • Purity
  • >98% by SDS-PAGE and HPLC analyses.
  • Storage
  • This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
  • Reconstitution
  • We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.

BACKGROUND

  • Antigen Description
  • GMF-β, a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto-immune diseases, possibly through its ability to induce the production and secretion of various pro-inflammatory cytokines.
  • Function
  • actin binding, enzyme activator activity, growth factor activity, protein kinase inhibitor activity, signal transducer activity.
  • Gene ID
  • 2764
  • Synonyms
  • GMF; GMF-beta; Glia maturation factor beta; glia maturation factor; beta

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