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Recombinant Human Interferon-β1b (CRP0889)

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Interferon-β1b CRP0889 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Human Interferon-β1b produced in E.coli is a single non-glycosylated polypeptide chain containing 165 amino acids and having a molecular mass of approximately 18.5 kDa.
  • Specificity
  • Fully biologically active when compared to standard. The specific activity as determined in a viral resistance assay is less then 0.03 ng/ml, corresponding to a specific activity of 4.0 x107IU/ mg.
  • Endotoxin
  • Less than 1EU/μg of rHuIFN-β1b as determined by LAL method.
  • Purity
  • >96% by SDS-PAGE and HPLC analyses.
  • Storage
  • This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
  • Reconstitution
  • We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
  • Recombinant Human Interferon-β1b
    PDB rendering based on 1au1. Available structures:1au1

BACKGROUND

  • Antigen Description
  • Interferon-beta is one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and immunomodulating activity. The synthesis of IFN-beta can be induced by common inducers of interferons, including viruses, double-stranded RNA, and micro-organisms. It is induced also by some cytokines such as TNF and IL-1.
  • Function
  • interferon-alpha/beta receptor binding
  • Gene ID
  • 3456
  • Synonyms
  • interferon beta 1; fibroblast; IFNB; IFB, IFF; IFNB_HUMAN; Interferon beta [Precursor]; IFN-beta; Fibroblast interferon;MGC96956;IFNB.

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