Recombinant Human Interleukin-11 (CRP0814)

Recombinant Human Interleukin-11 CRP0814 1mg Please Inquiry


  • Product Overview
  • The protein is produced in P. Pichia by recombinant DNA technology. The protein has a molecular mass of approximately 19,000 Daltons and is non-glycosylated. The protein is 177 amino acids in length and differs from the 178 amino acid length of native IL-11 only in lacking the amino-terminal praline residue.
  • Specificity
  • The ED50 as determined by the dose-dependant stimulation of the proliferation of murine 7TD1 was found to be less than 0.2ng/ml, corresponding to a Specific Activity of 1.0 x 106 IU/ mg.
  • Endotoxin
  • Less than 2ng/mg (2IEU/mg) determined by LAL test.
  • Purity
  • >95% as determined by SDS-PAGE and SEC-HPLC.
  • Storage
  • Lyophilized rHuIL-11 although stable at room temperature for 3 weeks, should be stored desiccated below -18oC. Upon reconstitution rHuIL-11 should be stored at 4oC between 2-7 days and for future use below -18oC. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Aliquot to avoid repeated freeze-thaw cycles.
  • Reconstitution
  • It is recommended to reconstitute the lyophilized rHuIL-11 in sterile 18MΩ-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.


  • Antigen Description
  • IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. IL-11 is a member of a family of human growth factors which includes human growth hormone, granulocyte colony-stimulating factor and other growth factors.
  • Function
  • cytokine activity, interleukin-11 receptor binding activity
  • Gene ID
  • 3589
  • Synonyms
  • AGIF; IL-11; Adipogenesis inhibitory factor, Oprelvekin, Interleukin-11.

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