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Recombinant Human Interleukin-15 (CRP0820)

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Interleukin-15 CRP0820 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Human IL-15 produced in E. coli is a single, non-glycosylated polypeptide chain containing 114 amino acids and having a molecular mass of 12774 Dalton.
  • Specificity
  • The ED50 as determined by the dose-dependant stimulation of the proliferation of CTLL-2 was found to be < 0.5 ng/ml, corresponding to a Specific Activity of 2.0 x 105 IU/ mg.
  • Endotoxin
  • Less than 0.1 ng/ug (IEU/ug) of rHuIL-15.
  • Purity
  • >98% as determined by RP-HPLC, FPLC and SDS-PAGE
  • Storage
  • Lyophilized rHuIL-15 although stable at room temperature for 3 weeks, should be stored desiccated below -18oC. Upon reconstitution rHuIL-15 should be stored at 4oC between 2-7 days and for future use below -18oC. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Aliquot to avoid repeated freeze-thaw cycles.
  • Reconstitution
  • It is recommended to reconstitute the lyophilized rHuIL-15 in sterile 18MΩ-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

BACKGROUND

  • Antigen Description
  • Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological functions, including stimulation and maintenance of cellular immune responses. IL-15 stimulates the proliferation of T-lymphocytes, which requires interaction of IL-15 with components of IL-2R, including IL-2R and probably IL-2R gamma, but not IL-2R.
  • Function
  • Hematopoietin/interferon-class; cytokine receptor binding; protein binding; signal transducer activity
  • Gene ID
  • 3600
  • Synonyms
  • IL-15, MGC9721, Interleukin-15 precursor.

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