Close

Services
- Services
  
  Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
  
  Highlights
  - Discovery Services
  - Engineering Services
Products
- - Premade Antibody & Peptide Libraries
    
    Premade Phage Display Antibody Libraries
    
    Yeast Display Human scFv Library
    
    Premade Phage Display Peptide Libraries
    
    Premade Single Domain Antibody Libraries
    
    Immunized Human Antibody Libraries
- Products
  With over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications.
  Highlights
  - sdAb Libraries
  - Immunized hAb Libraries
Platforms
- Platforms
  
  Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
  
  Highlights
  - B-Cell Sorting Platform
  - Phage Display Platform
Resources
- Resources
  
  With deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
  
  Highlights
  - Peer-Reviewed Publications
  - Support Documents
Careers
- Careers
  
  Creative Biolabs is one of the world’s leading contract organizations (CRO) that has extensive experience in preclinical drug discovery. Our employees are at the core of our success, with the ambition to improving health and increasing access to quality health solutions worldwide. We believe when curious, courageous and collaborative people like you are brought together, a big difference will be made for the development of innovate medicines.
About Us
- About Us
  
  Get a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
  
  Highlights
  - About CBL
  - Contact Us

Product Search Keyword Search

Close

Home
Long-R3-IGF-I
Recombinant Human Long Arg3 Insulin-like Growth Factor-I

Recombinant Human Long Arg3 Insulin-like Growth Factor-I

"Creative Biolabs is committed to providing highly customized comprehensive solutions with the best quality to advance our global clients’ projects."

Recombinant Human Long Arg3 Insulin-like Growth Factor-I (CRP0805)

Datasheet

DESCRIPTION	CATALOG #	SIZE	PRICE
Recombinant Human Long Arg3 Insulin-like Growth Factor-I	CRP0805	1mg	Please Inquiry

PRODUCT INFORMATION

Product Overview
Recombinant Human Long-R3-IGF-I produced in E. coli is a single, non-glycosylated, polypeptide chain containing 83 amino acids and having a molecular mass of 9.111 kDa.

Specificity
The ED50, calculated by the dose-dependant proliferation of murine BALB\C 3T3 cells is less than 1.0 ng/ml, corresponding to a specific activity of 1.0 x 10⁶ IU/mg. For most in-vitro applications, Long-R³-IGF-I exerts its biological activity in the concentration range of 0.2-20 ng/ml.

Endotoxin
Less than 0.1ng/ug (1IEU/ug) of Long-R³-IGF-I.

Purity
>95% by SDS-PAGE and RP-HPLC.

Storage
Lyophilized Long-R³-IGF-I although stable at room temperature for 3 weeks, should be stored desiccated below -18^oC. Upon reconstitution Long-R³-IGF-I should be stored at 4^oC between 2-7 days and for future use below -18^oC. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Aliquot to avoid repeated freeze-thaw cycles.

Reconstitution
It is recommended to reconstitute the lyophilized Long-R³-IGF-I in 500mM acetic acid not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

PDB rendering based on 1bqt.

BACKGROUND

Antigen Description
Human Long Arg3 Insulin-like Growth Factor-I (Long-R³-IGF-I) is an 83 amino acid analog of human IGF-I comprising the complete human IGF-I sequence with the substitution of an Arg for the Glu at position 3 (hence R³), and a 13 amino acid extension peptide at the N-terminus. Scientists have engineered this analog with the express purpose of increasing biological activity. Human Long-R3-IGF-I is significantly more potent than human IGF-I in vitro. The enhanced potency is due to the markedly decreased binding of human Long-R³-IGF-I to IGF binding proteins which normally inhibit the biological actions of IGFs.

Function
Growth factor activity, Hormone activity, Insulin-like growth factor receptor binding, Prothoracicotrophic hormone activity

Gene ID
3479

Synonyms
IBP1, IGF-IA, IGF-IB, IGFI, MGF, Somatomedin-C; Insulin-like growth factor IA precursor; Insulin-like growth factor IB precursor; Mechano growth factor; insulin-like growth factor 1

Related Products

All listed customized services & products are for research use only, not intended for pharmaceutical, diagnostic, therapeutic or any in vivo human use.

Online Inquiry

CONTACT US

	USA: 45-1 Ramsey Road, Shirley, NY 11967, USA Europe: Heidenkampsweg 58, 20097 Hamburg, Germany
	Call us at: USA: 1-631-381-2994 Europe: 44-207-097-1828 Fax: 1-631-207-8356
	Email:

Our customer service representatives are available 24 hours a day, 7 days a week.

Services
Platforms
Help & Support
Contact us
USA 45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email: Europe Heidenkampsweg 58, 20097 Hamburg, Germany
Tel: 44-207-097-1828
Email:
Subscribe to Our Newsletter for Updates: