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Recombinant Human Voltage Dependent Anion Channel-1 produced in E. coli has a molecular mass of approximately 32 KDa.
≥ 95% by SDS-PAGE.
Liquid. In 1% Acetic Acid.
VDAC forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel allows diffusion of small hydrophilic molecules; it adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has weak anion selectivity whereas the closed state is cation-selective. rh-VDAC is expressed in E. coli.
protein binding.voltage-gated anion channel activity
MGC111064; PORIN; PORIN-31-HL; VDAC; VDAC-1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; Voltage-dependent anion-selective channel protein 1; voltage-dependent anion channel 1