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- Altumomab-iFluor 750
Altumomab-iFluor 750 (CAT#: ADC-FL-947)
This product is comprised of an anti-CEACAM5 monoclonal antibody (Altumomab) labeled with iFluor 750. iFluor 750 is a near-IR-fluorescent dye and it's excitation/emission is 749/775 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CEACAM5
- Alternative Names
- CEACAM5; carcinoembryonic antigen-related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100; DKFZp781M2392;
- Overview
- This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
- Overview
- Humanized Anti-CEACAM5 IgG1 antibody, altumomab
- Generic name
- Altumomab
- Species Reactivity
- Human
- Name
- iFluor 750
- Color
- Near-IR
- Excitation⁄Emission (nm)
- 749/775
- Detection method
- Fluorescent
Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-2579 | Anti-CEACAM5-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-970 | Anti-CEACAM5 (Altumomab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-973 | Anti-CEACAM5 (Altumomab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-972 | Anti-CEACAM5 (Altumomab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-968 | Anti-CEACAM5 (Altumomab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
For Research Use Only. NOT FOR CLINICAL USE.
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