Aminooxy-PEG8-acid is a PEG derivative containing an aminooxy group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage.
- Description
- Aminooxy-PEG8-acid is a PEG derivative containing an aminooxy group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage.
- Functional Group 1
- NH2/Amine
- Cleavable/Non-cleavable
- Non-cleavable
- Group 2
- COOH/Carboxylic Acid
- Functional Group 2
- COOH/Carboxylic Acid
- Storage Condition
- -20 ° C
- Shipping
- Ambient Temperature
For Research Use Only. NOT FOR CLINICAL USE.
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