Anti-ANGPT2 MAb (Clone 1)-iFluor® 450 Succinimidyl Ester (WJY0-LS6732)

This product is comprised of an Human Anti-ANGPT2 IgG1 antibody (Clone 1) labeled with iFluor® 450 Succinimidyl Ester. iFluor® 450 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.

TARGET

Name
ANGPT2

Alternative Names
ANGPT2; AGPT2; ANG2; angiopoietin 2

Overview
The protein encoded by this gene is an antagonist of angiopoietin 1 (Ang-1), and both (Ang-1 and Ang-2) are ligands for the endothelial tyrosine kinase receptor (Tie2). These two ligands affect angiogenesis during embryogenesis and tumorigenesis. The encoded protein disrupts the vascular remodeling ability of Ang-1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.

ANTIBODY

Overview
Human Anti-ANGPT2 IgG1 antibody (Clone 1)

Species Reactivity
Human

DYE

Name
iFluor® 450 Succinimidyl Ester

Color
Green

Excitation⁄Emission (nm)
451/502

Detection method
Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.

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