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- Anti-ANGPT2 MAb (Clone 2)-iFluor® 440 Succinimidyl Ester
Anti-ANGPT2 MAb (Clone 2)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5688)
This product is comprised of an Human Anti-ANGPT2 IgG1-kappa (Clone 2) labeled with iFluor® 440 Succinimidyl Ester. iFluor® 440 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- ANGPT2
- Alternative Names
- ANGPT2; AGPT2; ANG2; angiopoietin 2
- Overview
- The protein encoded by this gene is an antagonist of angiopoietin 1 (Ang-1), and both (Ang-1 and Ang-2) are ligands for the endothelial tyrosine kinase receptor (Tie2). These two ligands affect angiogenesis during embryogenesis and tumorigenesis. The encoded protein disrupts the vascular remodeling ability of Ang-1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
- Overview
- Human Anti-ANGPT2 IgG1-kappa (Clone 2)
- Species Reactivity
- Human
- Name
- iFluor® 440 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 434/480
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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Published Data
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| CAT# | Product Name | Linker | Payload |
| ADC-W-665 | Anti-ANGPT2 MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-664 | Anti-ANGPT2 MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-662 | Anti-ANGPT2 SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-666 | Anti-ANGPT2 MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-667 | Anti-ANGPT2 MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
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