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- Anti-ANGPT2 MAb (Clone 3)-iFluor® 430 Succinimidyl Ester
Anti-ANGPT2 MAb (Clone 3)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4151)
This product is comprised of an Humanized Anti-ANGPT2 IgG1-lambda (Clone 3) labeled with iFluor® 430 Succinimidyl Ester. iFluor® 430 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- ANGPT2
- Alternative Names
- ANGPT2; AGPT2; ANG2; angiopoietin 2
- Overview
- The protein encoded by this gene is an antagonist of angiopoietin 1 (Ang-1), and both (Ang-1 and Ang-2) are ligands for the endothelial tyrosine kinase receptor (Tie2). These two ligands affect angiogenesis during embryogenesis and tumorigenesis. The encoded protein disrupts the vascular remodeling ability of Ang-1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
- Overview
- Humanized Anti-ANGPT2 IgG1-lambda (Clone 3)
- Species Reactivity
- Human
- Name
- iFluor® 430 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 433/498
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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Published Data
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| CAT# | Product Name | Linker | Payload |
| ADC-W-666 | Anti-ANGPT2 MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-663 | Anti-ANGPT2 SPDB-DM4 ADC ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-664 | Anti-ANGPT2 MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-667 | Anti-ANGPT2 MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-665 | Anti-ANGPT2 MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
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