Anti-ANGPT2 MAb (Clone 3)-iFluor® 450 Succinimidyl Ester
Anti-ANGPT2 MAb (Clone 3)-iFluor® 450 Succinimidyl Ester (WJY0-LS7227)
This product is comprised of an Humanized Anti-ANGPT2 IgG1-lambda (Clone 3) labeled with iFluor® 450 Succinimidyl Ester. iFluor® 450 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
TARGET
Name
ANGPT2
Alternative Names
ANGPT2; AGPT2; ANG2; angiopoietin 2
Overview
The protein encoded by this gene is an antagonist of angiopoietin 1 (Ang-1), and both (Ang-1 and Ang-2) are ligands for the endothelial tyrosine kinase receptor (Tie2). These two ligands affect angiogenesis during embryogenesis and tumorigenesis. The encoded protein disrupts the vascular remodeling ability of Ang-1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.