- Home
- Products
- Customized FluoroAb™
- APP
- Anti-APP MAb (Clone 12)-iFluor® 440 Succinimidyl Ester
Anti-APP MAb (Clone 12)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS4737)
This product is comprised of an Humanized Anti-APP IgG2-kappa (Clone 12) labeled with iFluor® 440 Succinimidyl Ester. iFluor® 440 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1; Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Humanized Anti-APP IgG2-kappa (Clone 12)
- Species Reactivity
- Human
- Name
- iFluor® 440 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 434/480
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-CD19 MAb (Clone 6)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS9629)
- Anti-IL17A MAb (Clone 5)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16692)
- Anti-CEACAM5 MAb (Clone 1)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS15572)
- Anti-LTA MAb (Clone 2)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5996)
- Anti-TNFRSF17 MAb (Clone 25)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7100)
- Anti-IL23A MAb (Clone 6)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10561)
- Anti-Rabies Virus Glycoprotein MAb (Clone 3)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15397)
- Anti-TNFRSF9 MAb (Clone 4)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS9214)
- Anti-LTA MAb (Clone 12)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15234)
- Anti-C5 MAb (Clone 4)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14673)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS4737. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-711 | Anti-APP (Ponezumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-702 | Anti-APP (Solanezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-714 | Anti-APP (Ponezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-712 | Anti-APP (Ponezumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-715 | Anti-APP (Ponezumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
