- Home
- Products
- Customized FluoroAb™
- APP
- Anti-APP MAb (Clone 19)-iFluor® 405 Succinimidyl Ester
Anti-APP MAb (Clone 19)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2623)
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1; Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Chimeric Humanized Anti-APP IgG4-kappa (Clone 19)
- Species Reactivity
- Human
- Name
- iFluor® 405 Succinimidyl Ester
- Color
- Blue
- Excitation⁄Emission (nm)
- 403/427
- Detection method
- Fluorescent
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS2623. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-704 | Anti-APP (Bapineuzumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-702 | Anti-APP (Solanezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-710 | Anti-APP (Ponezumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-715 | Anti-APP (Ponezumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-701 | Anti-APP (Solanezumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-EGFL7 MAb (Clone 1)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6354)
- Anti-HBV MAb (Clone 3)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4661)
- Anti-PCSK9 MAb (Clone 8)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS1444)
- Anti-FOLH1 MAb (Clone 7)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS600)
- Anti-IGHE MAb (Clone 9)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7453)
- Anti-FGFR2 MAb (Clone 9)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14101)
- Anti-ERBB2 MAb (Clone 16)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11197)
- Anti-191P4D12 MAb (Clone 1)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS3342)
- Anti-Thrombin inhibitor (BIBR_953) MAb (Clone 2)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS17020)
- Anti-IL13 MAb (Clone 5)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS1304)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
