- Home
- Products
- Customized FluoroAb™
- APP
- Anti-APP MAb (Clone 2)-iFluor® 350 Succinimidyl Ester
Anti-APP MAb (Clone 2)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS153)
This product is comprised of an Humanized Anti-APP IgG4-kappa antibody (Clone 2) labeled with iFluor® 350 Succinimidyl Ester. iFluor® 350 Succinimidyl Ester is a Blue-fluorescent dye and it's excitation/emission is 345/450 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1; Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Humanized Anti-APP IgG4-kappa antibody (Clone 2)
- Species Reactivity
- Human
- Name
- iFluor® 350 Succinimidyl Ester
- Color
- Blue
- Excitation⁄Emission (nm)
- 345/450
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-CD33 MAb (Clone 4)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14141)
- Anti-PCSK9 MAb (Clone 8)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10672)
- Anti-CD6 MAb (Clone 3)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7356)
- Anti-SLAMF7 MAb (Clone 3)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS6105)
- Anti-ITGA2B MAb (Clone 3)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10597)
- Anti-MS4A1 MAb (Clone 26)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7050)
- Anti-MUC16 MAb (Clone 10)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5286)
- Anti-CD2 MAb (Clone 3)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8790)
- Anti-APP MAb (Clone 5)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6308)
- Anti-ITIH4 MAb (Clone 1)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6498)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS153. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-707 | Anti-APP (Bapineuzumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-714 | Anti-APP (Ponezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-710 | Anti-APP (Ponezumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-701 | Anti-APP (Solanezumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-711 | Anti-APP (Ponezumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
