- Home
- Products
- Customized FluoroAb™
- APP
- Anti-APP MAb (Clone 20)-iFluor® 460 Succinimidyl Ester
Anti-APP MAb (Clone 20)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8776)
This product is comprised of an Human Anti-APP IgG1-kappa (Clone 20) labeled with iFluor® 460 Succinimidyl Ester. iFluor® 460 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1; Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Human Anti-APP IgG1-kappa (Clone 20)
- Species Reactivity
- Human
- Name
- iFluor® 460 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 468/493
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-ITGAV MAb (Clone 5)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11680)
- Anti-ERBB2 MAb (Clone 24)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5161)
- Anti-CD22 MAb (Clone 4)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS4942)
- Anti-FcRH5 MAb (Clone 3)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14152)
- Anti-Endotoxin MAb (Clone 4)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS13046)
- Anti-CXCR4 MAb (Clone 2)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS9734)
- Anti-APP MAb (Clone 18)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5698)
- Anti-ANGPTL3 MAb (Clone 2)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15478)
- Anti-IGF1R MAb (Clone 3)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8302)
- Anti-IL17A MAb (Clone 8)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS9005)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS8776. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-713 | Anti-APP (Ponezumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-710 | Anti-APP (Ponezumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-712 | Anti-APP (Ponezumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-701 | Anti-APP (Solanezumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-705 | Anti-APP (Bapineuzumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
