- Home
- Products
- Customized FluoroAb™
- C5
- Anti-C5 MAb (Clone 1)-iFluor® 546 Succinimidyl Ester
Anti-C5 MAb (Clone 1)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14424)
- TARGET
- ANTIBODY
- DYE
- Name
- C5
- Alternative Names
- C5; complement component 5; complement C5; CPAMD4; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; FLJ17816; FLJ17822; MGC142298;
- Overview
- This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.
- Overview
- Humanized Anti-C5 IgG2/G4-kappa antibody (Clone 1)
- Species Reactivity
- Human
- Name
- iFluor® 546 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 541/557
- Detection method
- Fluorescent
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS14424. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-732 | Anti-C5 (Eculizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-728 | Anti-C5 (Eculizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-735 | Anti-C5 (Pexelizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-733 | Anti-C5 (Eculizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-731 | Anti-C5 (Eculizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-IGF1 MAb (Clone 6)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15127)
- Anti-MSTN MAb (Clone 12)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10659)
- Anti-MYL MAb (Clone 8)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12375)
- Anti-VEGFA MAb (Clone 6)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS6159)
- Gomiliximab-OGreen (CAT#: ADC-FL-1475)
- Anti-IL5 MAb (Clone 2)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11401)
- Anti-C. diff Toxin A MAb (Clone 1)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6888)
- Anti-CD6 MAb (Clone 7)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2746)
- Anti-CD2 MAb (Clone 3)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2638)
- Anti-ERBB2 MAb (Clone 39)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10139)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
