- Home
- Products
- Customized FluoroAb™
- C5
- Anti-C5 MAb (Clone 19)-iFluor® 450 Succinimidyl Ester
Anti-C5 MAb (Clone 19)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6263)
This product is comprised of an Humanized Anti-C5 scFv antibody (Clone 19) labeled with iFluor® 450 Succinimidyl Ester. iFluor® 450 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- C5
- Alternative Names
- C5; complement component 5; complement C5; CPAMD4; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; FLJ17816; FLJ17822; MGC142298;
- Overview
- This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.
- Overview
- Humanized Anti-C5 scFv antibody (Clone 19)
- Species Reactivity
- Human
- Name
- iFluor® 450 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 451/502
- Detection method
- Fluorescent
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS6263. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-736 | Anti-C5 (Pexelizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-737 | Anti-C5 (Pexelizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-738 | Anti-C5 (Pexelizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-730 | Anti-C5 (Eculizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-731 | Anti-C5 (Eculizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-FcRH5 MAb (Clone 6)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11722)
- Anti-IGF1R MAb (Clone 3)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5226)
- Anti-MET MAb (Clone 18)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS6025)
- Anti-EGFR MAb (Clone 16)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14391)
- Anti-integrin alpha(v)beta(3) MAb (Clone 2)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16754)
- Anti-FOLR1 MAb (Clone 8)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS13305)
- Anti-IL23A MAb (Clone 5)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS13636)
- Anti-TNFSF13B MAb (Clone 5)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12300)
- Anti-FGFR2 MAb (Clone 12)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS7952)
- PRO 140-OGreen (CAT#: ADC-FL-359)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
