Anti-CD33 MAb (Clone 9)-iFluor® 450 Succinimidyl Ester
Anti-CD33 MAb (Clone 9)-iFluor® 450 Succinimidyl Ester (WJY0-LS6967)
This product is comprised of an Humanized Anti-CD33 IgG4 kappa antibody,Gemtuzumab) (Clone 9) labeled with iFluor® 450 Succinimidyl Ester. iFluor® 450 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
CD33 or Siglec-3 is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. It binds sialic acids, therefore is a member of the SIGLEC family of lectins.