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- Anti-CD3D MAb (Clone 1)-iFluor® 514 Succinimidyl Ester
Anti-CD3D MAb (Clone 1)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS10937)
This product is comprised of an Humanized Anti-CD3D IgG1-kappa antibody (Clone 1) labeled with iFluor® 514 Succinimidyl Ester. iFluor® 514 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD3D
- Alternative Names
- CD3D; CD3d molecule; delta (CD3-TCR complex); CD3d antigen; delta polypeptide (TiT3 complex) ; T3D; T-cell surface glycoprotein CD3 delta chain; CD3 delta; OKT3; delta chain; CD3 antigen; delta subunit; T-cell receptor T3 delta chain; CD3d antigen; delta polypeptide (TiT3 complex); T3D; CD3-DELTA
- Overview
- The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
- Overview
- Humanized Anti-CD3D IgG1-kappa antibody (Clone 1)
- Species Reactivity
- Human
- Name
- iFluor® 514 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 511/527
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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| CAT# | Product Name | Linker | Payload |
| ADC-W-830 | Anti-CD3D (Teplizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-835 | Anti-CD3D (Teplizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-833 | Anti-CD3D (Teplizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-832 | Anti-CD3D (Teplizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-834 | Anti-CD3D (Teplizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
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