This product is comprised of an Humanized Anti-CD4 IgG4-kappa antibody (Clone 6) labeled with iFluor® 430 Succinimidyl Ester. iFluor® 430 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
TARGET
- Alternative Names
- CD4; CD4 molecule; CD4 antigen (p55) ; T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
- Overview
- This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
ANTIBODY
- Overview
- Humanized Anti-CD4 IgG4-kappa antibody (Clone 6)
DYE
- Name
- iFluor® 430 Succinimidyl Ester
- Excitation⁄Emission (nm)
- 433/498
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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