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- Anti-CD40LG MAb (Clone 1)-iFluor® 405 Succinimidyl Ester
Anti-CD40LG MAb (Clone 1)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS1722)
This product is comprised of an Humanized Anti-CD40L IgG1-kappa antibody 1 (Clone 1) labeled with iFluor® 405 Succinimidyl Ester. iFluor® 405 Succinimidyl Ester is a Blue-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD40LG
- Alternative Names
- CD40LG; CD40 ligand; HIGM1; IMD3; TNFSF5; tumor necrosis factor (ligand) superfamily; member 5 (hyper IgM syndrome); CD40 antigen ligand; CD40L; CD154; gp39; hCD40L; hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; TRAP; internalized inside cells; the cytosol provides reducing environment including intracellular enzyme protein disulfide isomerase; or similar enzymes; drugs can be released.
- Overview
- The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
- Overview
- Humanized Anti-CD40L IgG1-kappa antibody 1 (Clone 1)
- Species Reactivity
- Human
- Name
- iFluor® 405 Succinimidyl Ester
- Color
- Blue
- Excitation⁄Emission (nm)
- 403/427
- Detection method
- Fluorescent
Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-2448 | Anti-CD40LG (Dapirolizumab pegol)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-921 | Anti-CD40LG (Toralizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-2445 | Anti-CD40LG (Dapirolizumab pegol)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-920 | Anti-CD40LG (Toralizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-2449 | Anti-CD40LG (Dapirolizumab pegol)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
For Research Use Only. NOT FOR CLINICAL USE.
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