This product is comprised of an Humanized Anti-CD40L IgG1-kappa antibody 2 (Clone 2) labeled with iFluor® 514 Succinimidyl Ester. iFluor® 514 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
TARGET
- Alternative Names
- CD40LG; CD40 ligand; HIGM1; IMD3; TNFSF5; tumor necrosis factor (ligand) superfamily; member 5 (hyper IgM syndrome); CD40 antigen ligand; CD40L; CD154; gp39; hCD40L; hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; TRAP; tnternalized inside cells; the cytosol provides reducing environment including intracellular enzyme protein disulfide isomerase; or similar enzymes; drugs can be released.
- Overview
- The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
ANTIBODY
- Overview
- Humanized Anti-CD40L IgG1-kappa antibody 2 (Clone 2)
DYE
- Name
- iFluor® 514 Succinimidyl Ester
- Excitation⁄Emission (nm)
- 511/527
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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