Anti-CD6 MAb (Clone 12)-iFluor® 546 Succinimidyl Ester
Anti-CD6 MAb (Clone 12)-iFluor® 546 Succinimidyl Ester (WJY0-LS15055)
This product is comprised of an Humanized Anti-CD6 IgG1-kappa (Clone 12) labeled with iFluor® 546 Succinimidyl Ester. iFluor® 546 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.