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- Anti-CD70 MAb (Clone 11)-iFluor® 350 Succinimidyl Ester
Anti-CD70 MAb (Clone 11)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS874)
This product is comprised of an Humanized Anti-CD70 IgG1-lambda (Clone 11) labeled with iFluor® 350 Succinimidyl Ester. iFluor® 350 Succinimidyl Ester is a Blue-fluorescent dye and it's excitation/emission is 345/450 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD70
- Alternative Names
- CD70; CD70 molecule; CD27LG; TNFSF7; tumor necrosis factor (ligand) superfamily; member 7; CD70 antigen; CD27L; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily; member 7; CD27LG; TNFSF7;
- Overview
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
- Overview
- Humanized Anti-CD70 IgG1-lambda (Clone 11)
- Species Reactivity
- Human
- Name
- iFluor® 350 Succinimidyl Ester
- Color
- Blue
- Excitation⁄Emission (nm)
- 345/450
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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| ADC-W-573 | Anti-CD70-PBD ADC-6 | maleimidocaproyl-valine-alanine | pyrrolobenzodiazepine (PBD) |
| ADC-W-567 | Anti-CD70-DM1 ADC | Noncleavable thioether linker | DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-587 | Anti-CD70-Mc-VC-PABC-MMAE ADC-5 | MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE (Monomethyl auristatin E) |
| ADC-W-452 | Anti-CD70-Mc-MMAF ADC-1 | Mc (maleimidocaproyl) | MMAF (Monomethyl auristatin F) |
| ADC-W-953 | Anti-CD70-MC-Vc-PAB-MMAE ADC-7 | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
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