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- Anti-CEACAM5 MAb (Clone 11)-iFluor® 450 Succinimidyl Ester
Anti-CEACAM5 MAb (Clone 11)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7192)
- TARGET
- ANTIBODY
- DYE
- Name
- CEACAM5
- Alternative Names
- CEACAM5; carcinoembryonic antigen-related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100; DKFZp781M2392;
- Overview
- This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
- Overview
- Chimeric Anti-CEACAM5 IgG1-kappa (Clone 11)
- Species Reactivity
- Human
- Name
- iFluor® 450 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 451/502
- Detection method
- Fluorescent
Published Data
+ Submit Publications
Scientific Resources
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-2580 | Anti-CEACAM5-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-968 | Anti-CEACAM5 (Altumomab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-972 | Anti-CEACAM5 (Altumomab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-969 | Anti-CEACAM5 (Altumomab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-472 | Anti-CEACAM5-Phy-lys-SN-38 ADC | Phy-lys (Phenylalanine-lysine) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
For Research Use Only. NOT FOR CLINICAL USE.
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