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- Anti-CEACAM6 MAb (Clone 3)-iFluor® 514 Succinimidyl Ester
Anti-CEACAM6 MAb (Clone 3)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11990)
This product is comprised of an Humanized Anti-CEACAM6 IgG2-kappa (Clone 3) labeled with iFluor® 514 Succinimidyl Ester. iFluor® 514 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CEACAM6
- Alternative Names
- CEACAM6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); NCA; carcinoembryonic antigen-related cell adhesion molecule 6; CD66c; normal cross-reacting antigen; non-specific crossreacting antigen; CEAL;
- Overview
- This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.
- Overview
- Humanized Anti-CEACAM6 IgG2-kappa (Clone 3)
- Species Reactivity
- Human
- Name
- iFluor® 514 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 511/527
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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| CAT# | Product Name | Linker | Payload |
| ADC-W-977 | Anti-CEACAM6 (Sulesomab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-978 | Anti-CEACAM6 (Sulesomab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-974 | Anti-CEACAM6 (Sulesomab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-975 | Anti-CEACAM6 (Sulesomab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-979 | Anti-CEACAM6 (Sulesomab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
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