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- Anti-FAP MAb (Clone 1)-iFluor® 546 Succinimidyl Ester
Anti-FAP MAb (Clone 1)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14059)
- TARGET
- ANTIBODY
- DYE
- Name
- FAP
- Alternative Names
- FAP; fibroblast activation protein; alpha; seprase; DPPIV; integral membrane serine protease; 170 kDa melanoma membrane-bound gelatinase; FAPA; DKFZp686G13158;
- Overview
- The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Overview
- Humanized Anti-FAP IgG1-kappa antibody (Clone 1)
- Species Reactivity
- Human
- Name
- iFluor® 546 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 541/557
- Detection method
- Fluorescent
Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-1130 | Anti-FAP (Sibrotuzumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1135 | Anti-FAP (Sibrotuzumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1131 | Anti-FAP (Sibrotuzumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-1133 | Anti-FAP (Sibrotuzumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1134 | Anti-FAP (Sibrotuzumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
For Research Use Only. NOT FOR CLINICAL USE.
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