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- Anti-FAP MAb (Clone 4)-iFluor® 546 Succinimidyl Ester
Anti-FAP MAb (Clone 4)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14910)
This product is comprised of an Human Anti-FAP IgG1-kappa (Clone 4) labeled with iFluor® 546 Succinimidyl Ester. iFluor® 546 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- FAP
- Alternative Names
- FAP; fibroblast activation protein; alpha; seprase; DPPIV; integral membrane serine protease; 170 kDa melanoma membrane-bound gelatinase; FAPA; DKFZp686G13158;
- Overview
- The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Overview
- Human Anti-FAP IgG1-kappa (Clone 4)
- Species Reactivity
- Human
- Name
- iFluor® 546 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 541/557
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-1131 | Anti-FAP (Sibrotuzumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-593 | Anti-FAP-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2’-Deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1135 | Anti-FAP (Sibrotuzumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1133 | Anti-FAP (Sibrotuzumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1134 | Anti-FAP (Sibrotuzumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
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