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- Anti-FCER2 MAb (Clone 2)-iFluor® 546 Succinimidyl Ester
Anti-FCER2 MAb (Clone 2)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14061)
This product is comprised of an Chimeric Anti-FCER2 IgG1-kappa antibody (Clone 2) labeled with iFluor® 546 Succinimidyl Ester. iFluor® 546 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- FCER2
- Alternative Names
- FCER2; Fc fragment of IgE; low affinity II; receptor for (CD23); CD23A; Fc fragment of IgE; low affinity II; receptor for (CD23A) ; FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J; BLAST-2; CD23 antigen; fc-epsilon-RII;
- Overview
- The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Overview
- Chimeric Anti-FCER2 IgG1-kappa antibody (Clone 2)
- Species Reactivity
- Human
- Name
- iFluor® 546 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 541/557
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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| CAT# | Product Name | Linker | Payload |
| ADC-W-1139 | Anti-FCER2 (Lumiliximab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1145 | Anti-FCER2 (Gomiliximab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1141 | Anti-FCER2 (Lumiliximab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1146 | Anti-FCER2 (Gomiliximab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-1137 | Anti-FCER2 (Lumiliximab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
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