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- Anti-FZD1 MAb (Clone 2)-iFluor® 532 Succinimidyl Ester
Anti-FZD1 MAb (Clone 2)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS13568)
This product is comprised of an Chimeric Anti-FZD1 IgG1-kappa (Clone 2) labeled with iFluor® 532 Succinimidyl Ester. iFluor® 532 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- FZD1
- Alternative Names
- FZD1; frizzled family receptor 1; frizzled (Drosophila) homolog 1 ; frizzled 1; seven transmembrane spanning receptor ; frizzled homolog 1 (Drosophila); frizzled-1; DKFZp564G072; frizzled; Drosophila; homolog of; 1; Wnt receptor; fz-1; fzE1; hFz1;
- Overview
- Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
- Overview
- Chimeric Anti-FZD1 IgG1-kappa (Clone 2)
- Species Reactivity
- Human
- Name
- iFluor® 532 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 537/560
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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| CAT# | Product Name | Linker | Payload |
| ADC-W-1178 | Anti-FZD1 (Vantictumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1183 | Anti-FZD1 (Vantictumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1182 | Anti-FZD1 (Vantictumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-1180 | Anti-FZD1 (Vantictumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1179 | Anti-FZD1 (Vantictumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
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