- Home
- Products
- Customized FluoroAb™
- GD2
- Anti-GD2 MAb (Clone 3)-iFluor® 405 Succinimidyl Ester
Anti-GD2 MAb (Clone 3)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS3113)
This product is comprised of an Chimeric Anti-GD2 IgG1-kappa (Clone 3) labeled with iFluor® 405 Succinimidyl Ester. iFluor® 405 Succinimidyl Ester is a Blue-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- GD2
- Alternative Names
- Ganglioside GD2; GD2
- Overview
- GD2 is a disialoganglioside expressed in tumors of neuroectodermal origin (including human neuroblastoma and melanoma), and its expression in normal tissues (mainly human cerebellum and peripheral nerves) is highly restricted.
The relative tumor-specific expression of GD2 makes it a suitable target for immunotherapy using monoclonal antibodies or artificial T cell receptors. An example of such an antibody is hu14.18K322A, a monoclonal antibody. The anti-GD2 antibody is currently in phase II clinical trials for the treatment of previously untreated high-risk neuroblastoma and combined chemotherapy prior to stem cell transplantation and radiation therapy. A previous phase I clinical trial designed to reduce toxicity in patients with refractory or recurrent neuroblastoma found a safe dose and determined that common toxicity, especially pain, can be well controlled.
- Overview
- Chimeric Anti-GD2 IgG1-kappa (Clone 3)
- Species Reactivity
- Human
- Name
- iFluor® 405 Succinimidyl Ester
- Color
- Blue
- Excitation⁄Emission (nm)
- 403/427
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-IFNA1 MAb (Clone 3)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11552)
- Toralizumab-iFluor 555 (CAT#: ADC-FL-798)
- Anti-CD40 MAb (Clone 14)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4260)
- Anti-F3 MAb (Clone 7)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11623)
- Matuzumab-Bodipy FL (CAT#: ADC-FL-1146)
- Anti-TGFB2 MAb (Clone 3)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12272)
- Anti-TNFRSF17 MAb (Clone 13)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS382)
- Anti-Rabies Virus Glycoprotein MAb (Clone 1)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6872)
- Anti-BSG MAb (Clone 3)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS829)
- Anti-MSTN MAb (Clone 9)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7580)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS3113. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-2011 | Anti-GD2 (Dinutuximab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-2010 | Anti-GD2 (Dinutuximab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-2006 | Anti-GD2 (Dinutuximab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-2008 | Anti-GD2 (Dinutuximab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-2009 | Anti-GD2 (Dinutuximab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
