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- Anti-IL13 MAb (Clone 4)-iFluor® 555 Succinimidyl Ester
Anti-IL13 MAb (Clone 4)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16683)
- TARGET
- ANTIBODY
- DYE
- Name
- IL13
- Alternative Names
- Interleukin-13; P600; IL-13
- Overview
- This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
- Overview
- Humanized Anti-IL13 Fab-G1-kappa (Clone 4)
- Species Reactivity
- Human
- Name
- iFluor® 555 Succinimidyl Ester
- Color
- Yellow
- Excitation⁄Emission (nm)
- 557/570
- Detection method
- Fluorescent
Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-1302 | Anti-IL13 (Anrukinzumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-1298 | Anti-IL13 (Anrukinzumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1306 | Anti-IL13 (Lebrikizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1300 | Anti-IL13 (Anrukinzumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1304 | Anti-IL13 (Lebrikizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
For Research Use Only. NOT FOR CLINICAL USE.
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