Anti-IL20 MAb (Clone 1)-iFluor® 430 Succinimidyl Ester
Anti-IL20 MAb (Clone 1)-iFluor® 430 Succinimidyl Ester (WJY0-LS3870)
This product is comprised of an Human Anti-IL20 IgG4-kappa antibody (Clone 1) labeled with iFluor® 430 Succinimidyl Ester. iFluor® 430 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.